Microsoft discloses multiple spoofing flaws in Exchange Server and OfficePlus
Microsoft published security advisories for several spoofing vulnerabilities affecting Microsoft Exchange Server and Microsoft OfficePlus, identifying CVE-2021-41350, CVE-2021-42305, CVE-2022-41078, CVE-2022-41079, and CVE-2025-55243. The Exchange issues span multiple advisory releases and indicate a recurring class of flaws that could allow attackers to impersonate trusted senders, services, or content within enterprise messaging environments.
The disclosures show Exchange Server as the primary affected platform, with four separate spoofing CVEs listed across 2021 and 2022, while a later advisory extends the same risk category to OfficePlus. Although the referenced notices provide limited public technical detail, the affected products are widely deployed in corporate communications workflows, making spoofing weaknesses operationally significant for phishing, fraud, and trust-boundary bypass scenarios until patches are applied.

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How this story unfolded
4 events from the most recent confirmed update back to the earliest known activity.
Microsoft publishes advisory for CVE-2025-55243
Microsoft published a Security Update Guide entry for CVE-2025-55243, described as a Microsoft OfficePlus spoofing vulnerability.
Microsoft publishes advisories for CVE-2022-41078 and CVE-2022-41079
Microsoft released Security Update Guide entries for CVE-2022-41078 and CVE-2022-41079, both identified as Microsoft Exchange Server spoofing vulnerabilities.
Microsoft publishes advisory for CVE-2021-42305
Microsoft published Security Update Guide information for CVE-2021-42305, another Microsoft Exchange Server spoofing vulnerability.
Microsoft publishes advisory for CVE-2021-41350
Microsoft added CVE-2021-41350, a Microsoft Exchange Server spoofing vulnerability, to its Security Update Guide.
Sources
5 references tracked. Mallory keeps watching after this page renders.
CVE-2025-55243 - Security Update Guide - Microsoft - Microsoft OfficePlus Spoofing Vulnerability
msrc.microsoft.com
Open sourceCVE-2022-41079 - Security Update Guide - Microsoft - Microsoft Exchange Server Spoofing Vulnerability
msrc.microsoft.com
Open sourceCVE-2022-41078 - Security Update Guide - Microsoft - Microsoft Exchange Server Spoofing Vulnerability
msrc.microsoft.com
Open sourceCVE-2021-42305 - Security Update Guide - Microsoft - Microsoft Exchange Server Spoofing Vulnerability
msrc.microsoft.com
Open sourceCVE-2021-41350 - Security Update Guide - Microsoft - Microsoft Exchange Server Spoofing Vulnerability
msrc.microsoft.com
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